Schedule

DATE


08-Feb-22




15-Feb-22




22-Feb-22 




01-Mar-22




08-Mar-22



15-Mar-22



22-Mar-22




29-Mar-22 




05-Apr-22




12-Apr-22




19-Apr-22




26-Apr-22 




03-May-22




10-May-22




17-May-22




24-May-22




31-May-22 




07-Jun-22





14-Jun-22





Topic


AAV variants




Circuit tracing




Presynaptic inhibition




Basal Ganglia Network




Sensory Cortex






AAV variants




Engenieered virus-like particles




Targeted activation




Neuroanatomy




Spatial Sequencing




Targeting interneurons




Retrovirus




Cell profiling




Spatial Sequencing




Immune interactions




Long-term Rabies tracing




Flourescent labels





TBA





SPEAKER


Mohammadsharif Tabebordbar and Kim Lagerborg, Sabeti Laboratory, Harvard University

Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species

Cell: https://www.sciencedirect.com/science/article/pii/S0092867421010023?via%3Dihub


Patrick Aldrin-Kirk, Tomas Björklund Laboratory,

"A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants"; Stem Cell Reports: https://doi.org/10.1016/j.stemcr.2021.11.014


Bryan Coptis, Michale Bruchas Laboratory, University of Washington,

"A photoswitchable GPCR-based opsin for presynaptic inhibition"

Neuron: https://doi.org/10.1016/j.neuron.2021.04.026


Nicholas N. Foster, Hong-Wei Dong Laboratory, UCLA

"The mouse cortico–basal ganglia–thalamic network "

Nature: https://www.nature.com/articles/s41586-021-03993-3.pdf


Cameron Condylis, Jerry Chen Laboratory, Boston University

"Dense functional and molecular readout of a circuit hub in sensory cortex"

Science: https://www.science.org/doi/10.1126/science.abl5981


Postponed due to illness


David Goertsen, Viviana Gradinaru Laboratory, California Institute of Technology

"AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset " Nature Neuroscience: https://www.nature.com/articles/s41593-021-00969-4.pdf


Samagya Banskota and Aditya Raguram, David Liu Laboratory, MIT

"Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins"

Cell: https://www.cell.com/action/showPdf?pii=S0092-8674%2821%2901484-7


Debora Masini, Ole Kiehn Laboratory, Copenhagen University

"Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism"

Nature Communications: https://www.nature.com/articles/s41467-022-28075-4


Gregor Schuhknecht, Kevan Martin Laboratory, Zurich University

Structure and function of a neocortical synapse 

Nature: https://www.nature.com/articles/s41586-020-03134-2.pdf


Chun-Seok Cho, Jun Hee Lee Laboratory, University of Michigan

"Microscopic examination of spatial transcriptome using Seq-Scope"

Cell: https://www.sciencedirect.com/science/article/pii/S0092867421006279?via%3Dihub


Douglas Vormstein-Schneider and Jessica D. Lin, Jordane Dimidschstein Laboratory, MIT

"Viral manipulation of functionaly distinct interneurons"

Nature Neuroscience: https://www.nature.com/articles/s41593-020-0692-9


Michael Segel, Feng Zhang Laboratory, Broad Institute of MIT and Harvard

"Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery"

Science: DOI: 10.1126/science.abg6155


Lars E. Borm, Sten Linnarsson Laboratory, Karolinska Institutet

"Scalable in situ single-cell profiling by electrophoretic capture of mRNA"

BioRxiv: https://doi.org/10.1101/2022.01.12.476082


Ludvig Bergenståhle, Sci-life lab, KTH

"Super-resolved spatial transcriptomics by deep data fusion"

Nature Biotechnology: https://www.nature.com/articles/s41587-021-01075-3


Ian Clark, Cristia Gutierrez-Vazquez, Michael Wheeler, 

"Barcoded viral tracing of single-cell interactions in central nervous system inflammationy"

Science: DOI: 10.1126/science.abf1230


Lei Jin, Ian Wickersham Laboratory, MIT

Long-term labeling and imaging of synaptically-connected neuronal networks in vivo using nontoxic, double-deletion-mutant rabies viruses https://www.biorxiv.org/content/10.1101/2021.12.04.471186v1


Min Yen Lee and Chenyi Mao, Joshua C Vaughan Laboratory, University of Washington

Fluorescent labeling of abundant reactive entities (FLARE) for cleared-tissue and super-resolution microscopy (Nat Pro)

Feature-rich covalent stains for super-resolution and cleared tissue fluorescence microscopy (Sci Adv)

https://www.nature.com/articles/s41596-021-00667-2 and https://www.science.org/doi/10.1126/sciadv.aba4542


TBA